Nā hopena ʻaoʻao o Florfenicol

       ʻO FlorfenicolʻO ia kahi monofluoro synthetic derivative o ka thiamphenicol, ʻo ke ʻano molekala ʻo C12H14Cl2FNO4S, pauka crystalline keʻokeʻo a keʻokeʻo paha, ʻaʻohe ʻala, hoʻoheheʻe iki ʻia i ka wai a me ka chloroform, hoʻoheheʻe iki ʻia i ka waikawa acetic glacial, hoʻoheheʻe ʻia i ka Methanol, ethanol. He antibiotic ākea ākea hou ia o ka chloramphenicol no ka hoʻohana holoholona, ​​​​i hoʻomohala pono ʻia i ka hopena o nā makahiki 1980.

Ua kūʻai mua ʻia aku ia ma Iapana i ka makahiki 1990. I ka makahiki 1993, ua ʻāpono ʻo Norewai i ka lāʻau lapaʻau e mālama i ka furuncle o ka iʻa sālemona. I ka makahiki 1995, ua ʻāpono ʻo Palani, United Kingdom, Austria, Mekiko a me Sepania i ka lāʻau lapaʻau no ka mālama ʻana i nā maʻi bacteria hanu bipi. Ua ʻāpono ʻia hoʻi no ka hoʻohana ʻana ma ke ʻano he mea hoʻohui hānai no nā puaʻa ma Iapana a me Mekiko e pale aku a mālama i nā maʻi bacteria i nā puaʻa, a ua ʻāpono ʻo Kina i ka lāʻau lapaʻau.

He lāʻau antibiotic ia, kahi e hoʻopuka ai i kahi hopena bacteriostatic ākea ākea ma ke kāohi ʻana i ka hana o ka peptidyltransferase, a he ākea ka laulā antibacterial, me nā ʻano like ʻoleGram-maikaʻia me nā bacteria maikaʻi ʻole a me ka mycoplasma. ʻO nā bacteria koʻikoʻi e komo pū me ka bipi a me ka puaʻa ʻo Haemophilus,ʻO Shigella dysenteriae, Salmonella, Escherichia coli, Pneumococcus, Influenza bacillus, Streptococcus, Staphylococcus aureus, Chlamydia, Leptospira, Rickettsia, a pēlā aku. Hiki i kēia huahana ke hoʻolaha i loko o nā pūnaewele bacteria ma o ka lipid solubility, hana nui ma ka subunit 50s o ka bacterial 70s ribosome, kāohi i ka transpeptidase, keakea i ka ulu ʻana o ka peptidase, keakea i ka hoʻokumu ʻana o nā kaulahao peptide, no laila e pale ana i ka synthesis protein, e hoʻokō ana i ka pahuhopu Antibacterial. Hoʻopili koke ʻia kēia huahana e ka lawelawe waha, hoʻolaha nui ʻia, he hapalua ola lōʻihi, kiʻekiʻe ke koko o ka lāʻau lapaʻau, a lōʻihi ka manawa mālama koko.
I nā makahiki i hala iho nei, ua hoʻohana ka nui o nā mahi puaʻa liʻiliʻi a me ka waena i ka florfenicol no ka mālama ʻana me ka nānā ʻole i ke kūlana o nā puaʻa, a hoʻohana i ka florfenicol ma ke ʻano he lāʻau kilokilo. ʻO ka ʻoiaʻiʻo, he mea weliweli loa kēia. Loaʻa iā ia kahi hopena therapeutic maikaʻi i nā maʻi puaʻa i hoʻokumu ʻia e nā bacteria Gram-positive a me nā bacteria maikaʻi ʻole a me ka mycoplasma, ʻoi aku hoʻi ma hope o ka hui pū ʻana o ka florfenicol a me ka doxycycline, ua hoʻonui ʻia ka hopena, a he pono ia i ka mālama ʻana i ka puaʻa thoracic puaʻa atrophic rhinitis chain. ʻO Cocci, a pēlā aku, he hopena hoʻōla maikaʻi.
Eia nō naʻe, ʻo ke kumu he mea weliweli ka hoʻohana mau ʻana i ka florfenicol no ka mea he nui nā hopena ʻaoʻao o ka florfenicol, a ʻo ka hoʻohana lōʻihi ʻana i ka florfenicol e hana i ka ʻino ma mua o ka maikaʻi. No ka laʻana, ʻaʻole pono e hoʻowahāwahā nā hoaaloha puaʻa i kēia mau manaʻo.

1. Inā he mau maʻi viral e like me ka pseudorabies puaʻa fever me ke apo pepeiao polū ma ka mahi puaʻa, ʻo ka hoʻohana ʻana i ka florfenicol no ka mālama ʻana e lilo pinepine ia i mea kōkua o kēia mau maʻi viral, no laila inā loaʻa nā maʻi i luna a loaʻa ma hope. Ke loaʻa i nā maʻi puaʻa ʻē aʻe, mai hoʻohana i ka florfenicol no ka mālama ʻana, e hoʻonui ia i ka maʻi.
2. E hoʻopilikia ʻo Florfenicol i kā mākou ʻōnaehana hematopoietic a kāohi i ka hana ʻana o nā hunaola koko ʻulaʻula i loko o ka iwi iwi, ʻoiai inā he anu a pehu paha nā hono o kā mākou puaʻa waiū. ʻAʻole maikaʻi ke ʻano o ka lauoho puaʻa, he lauoho palai, akā hōʻike pū i nā hōʻailona o ka anemia, e hana pū i ka puaʻa ʻaʻole e ʻai lōʻihi, e hana ana i puaʻa paʻakikī.
3. He mea ʻawahia ka Florfenicol i ka embryo. Inā hoʻohana pinepine ʻia ka florfenicol i ka wā hāpai i nā puaʻa wahine, e hāʻule nā ​​​​puaʻa hua.
4. ʻO ka hoʻohana lōʻihi ʻana i ka florfenicol e hoʻoulu ai i nā maʻi gastrointestinal a me ka maʻi diarrhea i nā puaʻa.
5. He mea maʻalahi ke hana i ka maʻi lua, e like me ka dermatitis exudative i hoʻokumu ʻia e ka maʻi staphylococcus i loko o nā puaʻa a i ʻole ka maʻi lua o kekahi dermatitis fungal.
I ka hōʻuluʻulu ʻana, ʻaʻole pono e hoʻohana ʻia ka florfenicol ma ke ʻano he lāʻau maʻamau. Ke hoʻohana mākou i nā antibiotic ʻē aʻe me ka hopena maikaʻi ʻole a ma ke ʻano hui pū ʻia (expel virus), hiki iā mākou ke hoʻohana i ka florfenicol a me ka doxycycline ma ka ʻaoʻao. Hoʻohana ʻia ka Acupuncture e mālama i nā maʻi paʻakikī, a ʻaʻole ia e ʻōlelo ʻia no nā kūlana ʻē aʻe.