ʻO ka ʻike ʻana i kekahi mau kemika insecticidal, e like me nā mea pale namu, e pili ana me nā hopena maikaʻi ʻole i ke olakino, e like me kahi loiloi o ka ʻikepili noiʻi pekelala.
Ma waena o nā mea i komo i ka National Health and Nutrition Examination Survey (NHANES), ʻo ke kiʻekiʻe o ka ʻike ʻana i nā pesticides pyrethroid home i hoʻohana pinepine ʻia e pili ana me ka piʻi ʻekolu ʻana o ka make ʻana o nā maʻi cardiovascular (hazard ratio 3.00, 95% CI 1.02–8.80) i hōʻike ʻia e Kauka Wei Bao a me nā hoa hana mai ke Kulanui o Iowa ma Iowa City.
ʻO ka poʻe i ka tertile kiʻekiʻe loa o ka hōʻike ʻana i kēia mau pesticides, ua loaʻa iā lākou he 56% ka piʻi ʻana o ka pilikia o ka make mai nā kumu āpau i hoʻohālikelike ʻia me ka poʻe i ka tertile haʻahaʻa loa o ka hōʻike ʻana i kēia mau pesticides (RR 1.56, 95% CI 1.08–2. 26).
Eia nō naʻe, ua ʻike nā mea kākau ʻaʻole i pili nā insecticides pyrethroid me ka make ʻana o ka maʻi kanesa (RR 0.91, 95% CI 0.31–2.72).
Ua hoʻoponopono ʻia nā kumu hoʻohālike no ka lāhui/lāhui, ke kāne, ka makahiki, ka BMI, ka creatinine, ka ʻai, ke ʻano o ka nohona, a me nā kumu sociodemographic.
Ua ʻāpono ʻia nā lāʻau pepehi pepeke Pyrethroid no ka hoʻohana ʻana e ka US Environmental Protection Agency a hoʻohana pinepine ʻia i nā mea pale namu, nā mea pale ʻuku poʻo, nā shampoos holoholona a me nā sprays, a me nā huahana kaohi pest ʻē aʻe i loko a me waho a ua manaʻo ʻia he palekana.
"ʻOiai ua hana ʻia ma mua o 1,000 mau pyrethroids, aia wale nō ma kahi o ʻumikūmālua mau pesticides pyrethroid ma ka mākeke US, e like me permethrin, cypermethrin, deltamethrin a me cyfluthrin," wahi a ka hui a Bao, me ka hoʻohui ʻana ua "piʻi" ka hoʻohana ʻana i nā pyrethroids. "I nā makahiki i hala iho nei, ua ʻoi aku ka ʻino o ke kūlana ma muli o ka haʻalele mālie ʻana o ka hoʻohana ʻana i nā organophosphates i nā hale noho."
Ma kahi ʻōlelo hoʻopuka e pili pū ana, ua ʻōlelo ʻo Stephen Stellman, Ph.D., MPH, a me Jean Mager Stellman, Ph.D., o ke Kulanui ʻo Columbia ma New York, ʻo nā pyrethroids "ka lua o ka pesticide i hoʻohana nui ʻia ma ka honua, me ka huina o nā tausani kilokani a me nā ʻumi haneli miliona kālā US." Nā kūʻai aku US ma nā kālā US.
Eia kekahi, "ua nui nā pesticides pyrethroid a he mea hiki ʻole ke pale ʻia ka ʻike ʻia," kākau lākou. ʻAʻole ia he pilikia wale nō no nā limahana mahiʻai: "ʻO ka pīpī ʻana i nā makika ea e kāohi i ka maʻi West Nile a me nā maʻi ʻē aʻe i lawe ʻia e nā vector ma New York a ma nā wahi ʻē aʻe e hilinaʻi nui ʻia i nā pyrethroids," wahi a Stelmans.
Ua nānā ke aʻo ʻana i nā hopena o nā mea makua he 2,000 a ʻoi aku i komo i ka papahana NHANES 1999-2000 nāna i hoʻokolokolo kino, hōʻiliʻili i nā hāpana koko, a pane i nā nīnau noiʻi. Ua ana ʻia ka ʻike ʻia ʻana o Pyrethroid e nā pae mimi o ka 3-phenoxybenzoic acid, kahi metabolite pyrethroid, a ua māhele ʻia nā mea komo i nā tertiles o ka ʻike ʻia.
I ka wā o ka nānā ʻana he 14 mau makahiki, ua make he 246 mau mea komo: 52 mai ke kanesa a me 41 mai nā maʻi cardiovascular.
Ma ka awelika, ʻoi aku ka nui o ka pilikia o ka poʻe ʻeleʻele ʻaʻole Hispanic i nā pyrethroids ma mua o ka poʻe Hispanic a me ka poʻe keʻokeʻo ʻaʻole Hispanic. ʻO ka poʻe me ka loaʻa kālā haʻahaʻa, ka pae hoʻonaʻauao haʻahaʻa, a me ka maikaʻi ʻole o ka ʻai ʻana, ʻoi aku ka nui o ka pyrethroid i loaʻa iā lākou.
Ua hōʻike ʻo Stellman lāua ʻo Stellman i ka "hapalua ola pōkole loa" o nā biomarkers pyrethroid, ʻo ka awelika he 5.7 mau hola wale nō.
"ʻO ke alo o nā pae i ʻike ʻia o nā metabolites pyrethroid i hoʻopau koke ʻia i nā heluna kanaka nui a like ʻole o ka honua e hōʻike ana i ka hōʻike lōʻihi a he mea nui hoʻi e ʻike i nā kumu kaiapuni kikoʻī," wahi a lākou.
Eia nō naʻe, ua ʻike pū lākou no ka mea he ʻōpiopio nā makahiki o ka poʻe i komo i ke aʻo ʻana (20 a 59 mau makahiki), he paʻakikī ke kuhi piha i ka nui o ka pilina me ka make ʻana o ka maʻi cardiovascular.
Eia nō naʻe, ʻo ka "unusually high hazard quotient" e pono ai ka noiʻi hou aku i kēia mau kemika a me ko lākou mau pilikia olakino lehulehu, wahi a Stellman lāua ʻo Stellman.
ʻO kekahi palena o ke aʻo ʻana, e like me ka ʻōlelo a nā mea kākau, ʻo ia ka hoʻohana ʻana i nā hāpana mimi kula e ana i nā metabolites pyrethroid, ʻaʻole paha e hōʻike i nā loli i ka hala ʻana o ka manawa, e alakaʻi ana i ka hoʻokaʻawale hewa ʻana o ka ʻike maʻamau i nā pesticides pyrethroid.
He mea kākau kiʻekiʻe ʻo Kristen Monaco i loea i ka endocrinology, psychiatry a me nā nūhou nephrology. Aia ʻo ia ma ke keʻena ma New York a ua hana pū me ka hui mai ka makahiki 2015.
Ua kākoʻo ʻia ka noiʻi e nā National Institutes of Health (NIH) ma o ke Kikowaena Noiʻi Ola Kino o ke Kulanui o Iowa.
Ka manawa hoʻouna: Sep-26-2023