ʻO ka maʻi hanu puaʻa he maʻi paʻakikī ia e hoʻopilikia ai i nā mea mālama puaʻa.He paʻakikī ka etiology, heʻokoʻa nā pathogens, he ākea ka laha, a he paʻakikī ka pale a me ka mālamaʻana, e lawe mai ana i nā poho nui i nā mahi puaʻa.I kēia mau makahiki i hala iho nei, hōʻike pinepine ʻia nā maʻi hanu puaʻa puaʻa i nā maʻi huikau, no laila ua maʻa mākou e kapa ʻia ʻo ka maʻi hanu puaʻa.ʻO nā pathogens maʻamau ka Mycoplasma, Haemophilus parasuis, Actinobacillus pleuropneumoniae, pepeiao uliuli, circovirus a me ka maʻi puaʻa.
No ka pale ʻana a me ka mālama ʻana i nā maʻi hanu, he hopena maikaʻi ka tilmicosin
Hoʻokaʻawale nui ʻia nā pathogens respiratory o nā puaʻa i ka bacteria, viruses a me mycoplasma.No ka mycoplasma a me ka porcine infectious pleuropneumonia, ua hoʻomohala ka lāʻau antibiotic maʻamau i ke kūʻē, a ua hoʻohana pinepine ʻia kahi hanauna hou o nā lāʻau lapaʻau e pale a mālama i nā maʻi hanu puaʻa.No ka laʻana, ʻo tilmicosin, doxycycline, tyvalomycin, a me nā mea ʻē aʻe, me ka lāʻau lapaʻau Kina antiviral, he hopena koʻikoʻi.Ua hōʻike ʻia nā haʻawina e loaʻa ana i ka tilmicosin kahi hopena antiviral hapa, a he hopena maikaʻi ia i ka mālama ʻana i ka maʻi maʻi hanu porcine e pili ana me PRRS porcine.
TilmicosinLoaʻa i kahi kaʻina hana hohonu a he nui nā pōmaikaʻi o ka uhi pālua.
E like me kā mākou e ʻike ai, ʻo tilmicosin kekahi o nā lāʻau lapaʻau maikaʻi loa no ka mālama ʻana i nā maʻi hanu i loko o nā māla puaʻa.Eia nō naʻe, ʻaʻole kūlike nā hopena o nā tilmicosin like ʻole ma ka mākeke.No ke aha kēia?Pehea e hiki ai iā mākou ke hoʻokaʻawale i waena o lākou?Pehea ka ʻokoʻa?No ka tilmicosin, aneane like nā mea maka, a ʻaʻole nui ka ʻokoʻa.No ka hōʻike ʻana i ka hopena o ka huahana, hilinaʻi nui ia i kāna kaʻina hana.Ma ke kaʻina hana huahana, ʻo ka hoʻoikaika ʻana i ka hopena huahana maikaʻi aʻe i lilo i mea nui.ulu ulu.
kūlana kiʻekiʻetilmicosinpono e loaʻa i nā ʻano ʻehā: makemake ka puaʻa i ka ʻai, ka pale ʻana i ka ʻōpū, ka hemo ʻana o ka ʻōpū a me ka hoʻokuʻu lohi.
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Hoʻokaʻawale i ka helehelena
1. ʻO nā'āpana tilmicosin i uhiʻoleʻia he maikaʻi loa a he maʻalahi hoʻi e hoʻoheheʻe i ka lumi wela, aʻo nā'āpana tilmicosin i uhiʻia heʻoi aku ka mānoanoa a paʻakikī ke hoʻoheheʻe i ka lumi wela.
2. ʻO ka tilmicosin maikaʻi (e like me Chuankexin i uhi ʻia me nā microcapsules pālua) loaʻa nā ʻāpana like ʻole a poʻe.Ma keʻano laulā, ʻokoʻa ka nui a me ka like o nā ʻāpana o ka tilmicosin i uhi ʻia.
Hoʻokaʻawale i ka ʻono o ka waha (maikaʻi ka palatability)
Tilmicosinʻona ʻawaʻawa, a ʻaʻole kūpono ka tilmicosin i uhi ʻole ʻia no ka lawelawe waha.ʻO Tilmicosin me ka ʻono ʻawaʻawa i ka waha ʻaʻole i hoʻokō wale i kahi ʻano lāʻau i makemake ʻole ʻia, akā pili pū kekahi i ka hānai puaʻa a hoʻopōʻino nui.ʻO ka ʻōpala lāʻau.
E hoʻokaʻawale i ka solubility ʻōpū a me ka solubility enteric
1. Hoʻokaʻawale ʻia ka uhi ʻana o ka tilmicosin i loko o ka enteric (acid-resistant but not alkali-resistant) coating a me ka gastric-soluble (ʻaʻole acid- and alkali-resistant).E hoʻoheheʻe ʻia ka tilmicosin i uhi ʻia a hoʻokuʻu ʻia e ka gastric acid i loko o ka ʻōpū, a i ka wā i hoʻokuʻu ʻia ai ka lāʻau lapaʻau, e hoʻoulu ia i ka mucosa o ka ʻōpū e hūnā i ka wai ʻōpū, a hiki ke maʻalahi ka nui o ka wai ʻōpū. ke koko o ka ʻōpū a me ka ʻeha ʻōpū.Inā hoʻoheheʻe ʻia ka lāʻau lapaʻau i ka ʻōpū a hoʻokuʻu ʻia ma mua, e hoʻemi nui ʻia ka bioavailability o ka lāʻau.ʻO ka maʻamau, e hoʻemi ʻia ka maikaʻi o ka lāʻau i hoʻoheheʻe ʻia i loko o ka ʻōpū ma mua o 10% i hoʻohālikelike ʻia me ka mea i loko o ka ʻōpū.Hoʻonui nui kēia i ke kumukūʻai o ka lāʻau.
2. ʻO ka uhi komo (anti-acid akā ʻaʻole anti-alkali) Hiki ke hoʻoheheʻe ʻia ka uhi a hoʻokuʻu ʻia ma o ke kaiapuni o ka ʻōpū i hiki ʻole ke hoʻoheheʻe ʻia i loko o ke kaiapuni alkaline o ka ʻōpū, e pale ana i nā hopena ʻaoʻao like ʻole a me nā hopena cardiotoxic ma muli o ka hoʻokuʻu mua ʻana i ka ʻōpū.I ka manawa like, hoʻomaikaʻi ʻia ka bioavailability o ka lāʻau i loko o ka ʻōpū.Hoʻokuʻu wikiwiki i loko o ka ʻōpū.
Hoʻohana ʻo Enteric coating i nā mea a me nā kaʻina hana, a ʻokoʻa hoʻi ka hoʻokuʻu ʻana i ka ʻōpū.Hoʻoheheʻe ʻia ka uhi maʻamau a hoʻokuʻu ʻia i loko o ka ʻōpū o ka ʻōpū a me ka hopena o ka ʻōpū, he ʻokoʻa loa ia mai ka hopena o ka microcapsule coating pālua, a wikiwiki ka absorption rate i loko o ka ʻāpana ʻōpū.
Ka manawa hoʻouna: Mar-17-2022