ʻO ka ulu ʻana o ka manawa o ke kūʻē ʻana i nā pepeke pepeke a me ke olaola o nā mea lawe malaria nui, nā makika Anopheles, ma Uganda

Ke hoʻonui neimea pepehi lāʻau makeHoʻemi ke kū'ē i ka pono o ka kaohi vector. He mea nui ka nānā ʻana i ke kū'ē vector e hoʻomaopopo i kona ulu ʻana a hoʻolālā i nā pane kūpono. Ma kēia haʻawina, ua nānā mākou i nā ʻano o ke kū'ē insecticide, ka biology heluna kanaka vector, a me ka loli genetic e pili ana i ke kū'ē ma Uganda ma luna o ʻekolu makahiki mai 2021 a 2023. Ma Mayuga, ʻo Anopheles funestus ss ka ʻano nui, akā aia nā hōʻike o ka hybridization me nā ʻano An. funestus ʻē aʻe. Ua kiʻekiʻe iki ka infestation Sporozoite, a hiki i ka 20.41% i Malaki 2022. Ua ʻike ʻia ke kū'ē ikaika i nā pyrethroids ma 10 mau manawa o ka diagnostic concentration, akā ua hoʻihoʻi hapa ʻia ka susceptibility i ka hoʻāʻo synergy PBO.
Palapala ʻāina o nā wahi hōʻiliʻili namu ma ka ʻĀpana ʻo Mayuge. Hōʻike ʻia ka ʻĀpana ʻo Mayuge i ka ʻeleʻele. Ua hōʻailona ʻia nā kauhale kahi i hana ʻia ai nā hōʻiliʻili me nā hōkū polū. Ua hana ʻia kēia palapala ʻāina me ka hoʻohana ʻana i ka polokalamu manuahi a wehe ʻia ʻo QGIS mana 3.38.
Ua mālama ʻia nā makika a pau ma lalo o nā kūlana hoʻoulu makika maʻamau: 24–28 °C, 65–85% ka haʻahaʻa pili, a me kahi manawa kūlohelohe 12:12 o ke ao. Ua hānai ʻia nā ʻenuhe makika i loko o nā pā larval a hānai ʻia me ka tetramine ad libitum. Ua hoʻololi ʻia ka wai larval i kēlā me kēia lā ʻekolu a hiki i ka pupation. Ua mālama ʻia nā mākua i puka mai i loko o nā hale Bugdom a hānai ʻia i kahi hopena kō 10% no 3-5 mau lā ma mua o ka bioassay.
Make ma ka bioassay pyrethroid ma ke kahua F1. Make kiko o nā makika Anopheles i hōʻike ʻia i nā pyrethroids wale nō a i nā pyrethroids i hui pū ʻia me nā synergists. Hōʻike nā kaha hewa ma nā pakuhi kaha a me ke kolamu i nā manawa hilinaʻi e pili ana i ka hewa maʻamau o ka awelika (SEM), a hōʻike ʻo NA ʻaʻole i hana ʻia ka hoʻāʻo. Hōʻike ka laina ʻulaʻula kiko i ka pae make 90% ma lalo nei i hōʻoia ʻia ai ke kūʻē.
Hoʻokomo ʻia nā ʻikepili āpau i hana ʻia a kālailai ʻia paha i ka wā o kēia haʻawina i loko o ka ʻatikala i paʻi ʻia a me kāna mau faila ʻIke Hoʻohui.
Ua hoʻololi ʻia ka mana pūnaewele mua o kēia ʻatikala: Ua paʻi hewa ʻia ka mana mua o kēia ʻatikala ma lalo o ka laikini CC BY-NC-ND. Ua hoʻoponopono ʻia ka laikini i CC BY.