ʻO ka hoʻololi ʻana i ka manawa o ke kūʻē ʻana i ka insecticide a me ka biology o nā maʻi malaria nui, nā makika Anopheles, ma Uganda.

Ke piʻi neilāʻau lāʻau lāʻauhoʻemi ke kū'ē i ka pono o ka mana vector. He mea nui ka nānā ʻana i ke kūpaʻa vector no ka hoʻomaopopo ʻana i kona hoʻomohala ʻana a me ka hoʻolālā ʻana i nā pane kūpono. Ma kēia noiʻi ʻana, ua nānā mākou i nā ʻano o ke kūʻē ʻana i nā pepeke, vector population biology, a me nā ʻano like ʻole e pili ana i ke kūʻē ʻana ma Uganda i ʻekolu makahiki mai 2021 a 2023. Ma Mayuga, ʻo Anopheles funestus ss ka mea nui, akā aia nā hōʻike o ka hybridization me kekahi An. ʻano funestus. He kiʻekiʻe ka nui o ka maʻi Sporozoite, piʻi i ka 20.41% i Malaki 2022. Ua ʻike ʻia ke kūʻē ikaika i nā pyrethroids ma 10 mau manawa o ka ʻike diagnostic, akā ua hoʻihoʻi ʻia ka susceptibility i ka PBO synergy test.
Palapala ʻāina o nā kahua hōʻiliʻili namu ma ka Apana ʻo Mayuge. Hōʻike ʻia ka Apana Mayuge i ka ʻeleʻele. Ua kaha ʻia nā kauhale kahi i hōʻiliʻili ʻia ai me nā hōkū uliuli. Ua hana ʻia kēia palapala ʻāina me ka polokalamu manuahi a wehe ʻia ʻo QGIS version 3.38.
Mālama ʻia nā makika a pau ma lalo o nā kūlana moʻomeheu namu maʻamau: 24–28 °C, 65–85% haʻahaʻa haʻahaʻa, a he 12:12 mau lā maʻamau. Ua hānai ʻia nā ʻuala namu i loko o nā pā larval a hānai ʻia i ka tetramine ad libitum. Hoʻololi ʻia ka wai larval i kēlā me kēia ʻekolu lā a hiki i ka pupa. Ua mālama ʻia nā poʻe mākua i puka mai i loko o nā hīnaʻi ʻo Bugdom a hānai ʻia he 10% solution sugar no 3-5 mau lā ma mua o ka bioassay.
ʻO ka make ma ka pyrethroid bioassay ma ka pae F1. ʻIke ʻia ka make ʻana o nā makika Anopheles i nā pyrethroids wale nō a me nā pyrethroids i hui pū ʻia me nā synergists. Hōʻike nā pahu kuhi ma ka pahu a me nā kolamu i nā wā hilinaʻi e pili ana i ka hewa maʻamau o ka mean (SEM), a hōʻike ʻo NA ʻaʻole i hoʻokō ʻia ka hoʻāʻo. Hōʻike ka laina ʻāʻī ʻulaʻula i ka pae make ma lalo o 90% kahi i hōʻoia ʻia ai ke kūʻē.
Hoʻokomo ʻia nā ʻikepili a pau i hana ʻia a i ʻike ʻia i ka wā o kēia noiʻi ʻana i loko o ka ʻatikala i paʻi ʻia a me kāna mau faila ʻike hou.
Ua hoʻololi ʻia ka mana pūnaewele mua o kēia ʻatikala: Ua paʻi hewa ʻia ka mana kumu o kēia ʻatikala ma lalo o ka laikini CC BY-NC-ND. Ua hoʻoponopono ʻia ka laikini iā ​​CC BY.