ʻO ka nui o ka nui o ka maʻi ma waena o nā keiki mai 6 mahina a 10 mau makahiki he 2.7 no 100 kanaka-mahina ma ka wahi IRS a me 6.8 no 100 kanaka-mahina ma ka wahi hoʻomalu. Eia naʻe, ʻaʻohe ʻokoʻa koʻikoʻi o ka maʻi maʻi maʻi ma waena o nā kahua ʻelua i loko o nā mahina ʻelua (Iulai-ʻAukake) a ma hope o ke kau ua (Dekemapa-Pepeluali) (e nānā i ke Kiʻi 4).
Kaplan-Meier ke ola ola no na keiki mai ka makahiki 1 a hiki i ka 10 makahiki ma ka wahi a'o ma hope o 8 malama o ka hahai ana.
Ua hoʻohālikelike kēia haʻawina i ka laha ʻana o ka maʻi malaria a me nā hanana ma ʻelua mau ʻāpana me ka hoʻohana ʻana i nā hoʻolālā hoʻokele malaria i hoʻohui ʻia e loiloi i ka hopena hou o IRS. Ua hōʻiliʻili ʻia ka ʻikepili ma nā ʻāpana ʻelua ma o ʻelua mau anana cross-sectional a me kahi noiʻi ʻimi noiʻi passive 9 mau mahina ma nā keʻena olakino. Ua hōʻike ʻia nā hualoaʻa mai nā noiʻi cross-sectional i ka hoʻomaka a me ka hopena o ke kau hoʻoili ʻana i ka maʻi malaria i ka haʻahaʻa haʻahaʻa loa ma ka apana IRS (LLTID+IRS) ma mua o ka apana hoʻomalu (LLTIN wale nō). Ma muli o ka hoʻohālikelike ʻana o nā ʻāpana ʻelua e pili ana i ka maʻi maʻi maʻi malaria a me nā interventions, hiki ke wehewehe ʻia kēia ʻokoʻa e ka waiwai hoʻohui o IRS ma ka moku IRS. ʻO ka ʻoiaʻiʻo, ʻike ʻia nā ʻupena insecticidal lōʻihi a me IRS e hōʻemi nui i ka kaumaha maʻi malaria ke hoʻohana wale ʻia. No laila, he nui nā haʻawina [7, 21, 23, 24, 25] e wānana i ko lākou hui ʻana e hopena i ka hōʻemi nui ʻana o ka maʻi maʻi ma mua o ka mea hoʻokahi. ʻOiai ʻo IRS, piʻi ka Plasmodium parasitaemia mai ka hoʻomaka ʻana a hiki i ka hopena o ke kau ua ma nā wahi me ka maʻi maʻi maʻi maʻi, a manaʻo ʻia e piʻi kēia ʻano ma ka hopena o ke kau ua. Eia nō naʻe, ʻoi aku ka haʻahaʻa o ka piʻi ʻana o ka wahi IRS (53.0%) ma mua o ka ʻāpana o ka mana (220.0%). ʻEiwa mau makahiki o nā hoʻolaha IRS i kōkua ʻole i ka hōʻemi a i ʻole ke kāohi ʻana i nā kiʻekiʻe o ka hoʻouna ʻana i nā maʻi ma nā wahi IRS. Eia kekahi, ʻaʻohe ʻokoʻa o ka helu gametophyte ma waena o nā wahi ʻelua i ka hoʻomaka. I ka pau ʻana o ke kau ua, ʻoi aku ka kiʻekiʻe o ka pae hoʻomalu (11.5%) ma mua o ka pūnaewele IRS (3.2%). Hōʻike ʻia kēia ʻike i ka haʻahaʻa haʻahaʻa loa o ka malaria parasitemia ma ka ʻāina IRS, ʻoiai ʻo ka gametocyte index kahi kumu kumu o ka maʻi makika e alakaʻi ana i ka maʻi malaria.
Hōʻike nā hopena o ka loiloi logistic regression i ka pilikia maoli e pili ana i ka maʻi maʻi maʻi ma ka wahi hoʻomalu a hōʻike i ka nui o ka hui ma waena o ke kuni a me ka parasitemia a ʻo ka anemia he kumu hoʻohilahila.
E like me ka parasitemia, ʻoi aku ka haʻahaʻa o ka maʻi malaria ma waena o nā keiki 0-10 makahiki ma ka IRS ma mua o nā wahi hoʻomalu. Ua ʻike ʻia nā kiʻekiʻe o ka hoʻouna kuʻuna ma nā wahi ʻelua, akā ua haʻahaʻa loa lākou ma ka IRS ma mua o ka wahi hoʻomalu (Figure 3). ʻOiaʻiʻo, ʻoiai e mau ana nā pesticides ma kahi o 3 mau makahiki ma LLINs, mau lākou a hiki i 6 mau mahina ma ka IRS. No laila, mālama ʻia nā hoʻolaha IRS i kēlā me kēia makahiki e uhi i nā piko hoʻouna. E like me ka mea i hōʻike ʻia e nā ʻāpana ola o Kaplan–Meier (Figure 4), ʻoi aku ka liʻiliʻi o nā maʻi maʻi maʻi maʻi maʻi maʻi maʻi maʻi maʻi o nā keiki ma nā wahi mālama. Kūlike kēia me nā haʻawina ʻē aʻe i hōʻike i nā hōʻemi nui o ka maʻi maʻi malaria ke hui pū ʻia ka IRS me nā hana ʻē aʻe. Eia naʻe, ʻo ka lōʻihi o ka pale ʻana mai nā hopena koena o IRS e hōʻike ana e pono e hoʻomaikaʻi ʻia kēia hoʻolālā ma o ka hoʻohana ʻana i nā insecticides lōʻihi a i ʻole ka hoʻonui ʻana i ka pinepine o ka noi.
ʻO nā ʻokoʻa o ka laha ʻana o ka anemia ma waena o IRS a me nā wahi hoʻomalu, ma waena o nā hui makahiki like ʻole a ma waena o nā poʻe me ka maʻi kuni a me ka ʻole o ke kuni hiki ke lilo i hōʻailona kūpono ʻole o ka hoʻolālā i hoʻohana ʻia.
Hōʻike kēia haʻawina e hiki i ka pirimiphos-methyl IRS ke hoʻemi nui i ka maʻi maʻi maʻi i nā keiki ma lalo o 10 mau makahiki o ka pyrethroid-resistant ʻo Koulikoro, a ʻo nā keiki e noho ana ma nā wahi IRS e ulu aʻe ka maʻi malaria a noho ʻole i ka malaria. lōʻihi ma ka ʻāina. Ua hōʻike ʻia nā haʻawina ʻo ka pirimiphos-methyl he insecticide kūpono no ka mālama ʻana i ka maʻi malaria ma nā wahi i maʻamau ka pale pyrethroid.
Ka manawa hoʻouna: Dec-09-2024